Safety Information

Erectile dysfunction is the inability to obtain or maintain an erection that is strong enough for sexual activity, including sexual intercourse. Approximately 52% of men older than 40 years old and 26% of men less than 40 years old have some degree of erectile dysfunction. Many situations can interfere with a normal erectile function, including stress, depression, anxiety, low testosterone, smoking, physical inactivity, and the use of alcohol and/or drugs. Other causes for ED can include an underlying cardiovascular condition or atherosclerosis.

• Vardenafil Levitra is a prescription medication for erectile dysfunction.
• It works by increasing blood flow to the penis.
• Vardenafil is marketed under the brand name Levitra.
• It typically takes about 25-60 minutes to work.
• The effects of vardenafil last up to 4-5 hours.
• It should be taken on an empty stomach for faster results.
• Common side effects include headache and flushing.
• Vardenafil is contraindicated with nitrates.
• Do not consume alcohol with vardenafil.
• Always follow your doctor's dosage instructions.

For example, obstructed or narrowed blood vessels can make it difficult for an erection to occur.

The purpose of Vardenafil is to relax restricted or narrowed blood vessels and relax smooth muscles in the phallus in order for an erection to be achieved.

Database of Abstracts of Reviews of Effects (DARE): Quality-assessed Reviews [Internet].

24/7 Physician Phone Access Online Follow Up Visits Research Supported Protocols No Waiting Rooms 5 Star Google Reviews Vardenafil is the active ingredient in Levitra. Vardenafil is a prescribed drug that is used primarily to treat erectile dysfunction (ED), also known as impotence, which is the inability to get or maintain an erection satisfactory for intercourse. Clinical studies have found Vardenafil to be highly effective for the treatment of ED in patients who have diabetes, hypertension, and dyslipidemia (high cholesterol). Further studies revealed that men with low testosterone as well as ED respond well to Vardenafil in combination with a testosterone replacement regimen. Clinical studies have found Vardenafil to be highly effective for the treatment of ED in patients who have diabetes, hypertensions, and dyslipidemia (high cholesterol).

The international index of erectile function (IIEF): a multidimensional scale for assessment of erectile dysfunction

The process of achieving an erection is complex. The first step is for a man to experience sexual arousal or an erotic stimulus. This arousal signals a cascade of events that relaxes cavernosal artery smooth muscles in the phallus. Parasympathetic nerves in the phallus release nitric oxide (N.O. ), which increases cyclic GMP (cGMP), decreases intracellular calcium levels, and enhances smooth muscle relaxation. Vardenafil specifically aims to address blood vessel-related erectile dysfunction by enhancing blood flow, relaxing cavernosal smooth muscle and increasing intracavernosal pressure resulting in a firm, rigid, and natural erection. Vardenafil is one example of a type of drug known as a PDE-5 inhibitor (phosphodiesterase). PDE-5 inhibitors prevent the breakdown of nitric oxide, a potent vasodilator that is necessary to maintain a rigid and firm erection. Taking Vardenafil typically results in increased NO in the penile cavernosal tissue and muscles, which ensures a prolonged, stronger, more easily attained erection. (There are several inactive ingredients, too.) Levitra is a brand name of the drug, whereas Vardenafil is the generic ingredient that can often be obtained in compound or at a more affordable price. Levitra is specifically marketed for the on-demand treatment of ED.

Swallow the medication whole or allow it to dissolve underneath your tongue, with or without food.

Vardenafil takes effect quickly, as soon as 10 minutes of taking a dose, though more levitra 20 mg tablet typically within 30 minutes. For maximum benefit, take your dose within 30-60 minutes of sexual activity. The effects of Vardenafil can last up to eight (8) hours, though in rare instances in may last for up to 12 hours.

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The drug will be comarketed by Glaxo Smith Kline and Bayer, and Bloomberg News reports packaging will feature the "Levitra flame" to help distinguish the round orange pills from Viagra's now-famous blue diamond-shaped ones. Both drugs are likely to soon have a third competitor stateside. Eli Lilly & Co and Icos Corporation intend to introduce tadalafil (Cialis®), another phosphodiesterase inhibitor, to the US market later this year. Tadalafil and vardenafil have both been approved in Europe. Currently, there have been no head-to-head trials comparing effectiveness of the three drugs.

Storage and Handling

A fourth oral erectile-dysfunction drug, apomorphine (Uprima®, TAP Pharmaceuticals), has been approved in Europe, and TAP Pharmaceuticals applied to the FDA for its approval at the end of 2002. It is a dopamine receptor agonist and works through an entirely different mechanism. Although the drug received the support of generic levitra without rx an FDA advisory panel in April 2000 (as reported by heartwire ), TAP Pharmaceuticals withdrew apomorphine's new drug application soon after, due to concerns that it caused fainting spells. It resubmitted the drug late last year after further studies. Cite this: FDA approves new erectile dysfunction drug - Medscape - Aug 20, 2003. There are four types of oral PDE-5 inhibitors that help treat ED and are currently approved by the U.S. Food and Drug Administration (FDA). These PDE-5 inhibitors work along the same pathway in the penis to promote smooth muscle relaxation and blood vessel dilation by increasing nitric oxide in the penis.

Side Effects

Effective birth control is recommended during cancer treatment. Even if you are not producing sperm, you could still be fertile and conceive. Washington, DC - The FDA gave approval yesterday to vardenafil (Levitra®, Bayer and Glaxo Smith Kline), an oral erectile-dysfunction drug that works through the same mechanism as sildenafil (Viagra®, Pfizer). Like sildenafil, vardenafil can seriously affect blood pressure and should not be taken by those on alpha blockers or nitrates. The recommended dose is 10 mg taken one hour before sexual activity, with 20-, 5.0-, and 2.5-mg doses available.

ED Prescriptions for $1-2 Per Pill

Vardenafil is a phosphodiesterase inhibitor and, like sildenafil, is strongly contraindicated if patients are taking nitrates (nitroglycerin tablets or patches) or alpha blockers, due to the possibility of a steep drop in blood pressure. Patients with QT prolongation are also advised not to take the drug, as there is a possibility of abnormal heart rhythm in these patients. The FDA warns that men whose underlying cardiovascular status makes sexual activity inadvisable should not take vardenafil. Patients who have suffered an MI or stroke within the last six months or have hypotension or hypertension, unstable angina, severe liver impairment, end-stage renal disease requiring dialysis, or retinitis pigmentosa should not take the drug. "Today's approval of Levitra means there is now an important alternative in the treatment of erectile dysfunction," said Colin J Foster, president, Bayer Pharmaceuticals Corporation, in a press release. These drugs work in the same way, but differ in immediacy of action, half-life, side effect profile, and other characteristics. These slight differences may benefit some men and be ineffective for others.

Levitra (Generic Vardenafil) Overview

The relaxation of smooth muscle in the phallus allows for an influx of arterial blood, increased intracavernosal pressure, and erectile expansion and rigidity. Increased venous outflow, a passive process, maintains the phallus in an erect state. When arousal has subsided, sympathetic nerves release norepinephrine, which stimulates alpha-adrenergic receptors. The resulting smooth muscle contraction causes the erection to reduce price levitra 10mg in size in rigidity. Nitric oxide and cGMP are essential components for smooth muscle relaxation in the phallus and vascular dilation.

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Without enough nitric oxide or cGMP, not enough blood can flow to the phallus for an erection. Phosphodiesterase (PDE) enhances the breakdown of nitric oxide (N.O) and reduces the presence of cGMP. There are several types of PDE enzymes, but PDE-5 is the primary PDE enzyme in the male phallus. By preventing or inhibiting PDE-5, cGMP can maintain blood flow by increasing N.O. All oral ED medications, including Vardenafil (Levitra), are PDE-5 inhibitors. Vardenafil (Levitra) was approved in 2003 for the U.S. market.

Overdose/Missed Dose

Patient assistance may be available to qualifying individuals without prescription drug coverage through the pharmaceutical company that makes the medication. Your provider can help you find these resources if they are available. There are a few side effects experienced with vardenafil. Talk to your provider if you have concerns about these side effects. Do not take a higher dose of vardenafil than your provider orders for you.

Contraindications for Levitra and Stendra?

Headache, facial flushing, stuffy or runny nose, and upset stomach. Less frequent side effects include blurry vision, a bluish hue to the field of vision, difficulty telling the difference between the colors blue and green, sensitivity to light, or a sudden loss of vision or hearing. If you have any of the following while using vardenafil, call 911 right away: An erection lasting more than 4 hours. Chest, arm, or neck pain, or nausea during sexual activity. Remember, vardenafil does not protect against sexually transmitted infections (STIs) or prevent pregnancy. It is known for its fast onset–Vardenafil can start working as quickly as 10 minutes after taking a dose. For maximum benefit, wait 30-60 minutes before sexual activity. Typically, Vardenafil stops working about eight (8) hours after taking a full dose, though its effects can last for up to 12 hours in some men. The biggest different between Vardenafil and other PDE-5 inhibitors is that Vardenafil can increase QT prolongation, which can lead to irregular heartbeats. If you have prolonged QTc or are currently taking Class 1 or Class 3 antiarrhythmics, you may consider a different ED drug.

• Levitra is manufactured by Bayer Pharmaceuticals.
• It is available in both tablet and generic forms.
• The drug can be prescribed for men aged 18 and above.
• Levitra's active ingredient is vardenafil hydrochloride.
• It helps achieve erections suitable for sexual activity.
• Taking fatty meals may delay the drug's onset.
• Levitra does not protect against sexually transmitted diseases.
• Use with caution if you have heart conditions.
• It is essential to inform your doctor of all medications.
• Vardenafil does not cure ED; it manages symptoms.

Let your healthcare provider know about any cardiac history before starting any ED medication. A doctor will assess your current health and your potential side effects when considering what type of ED medication is best for you. You may also have some input when choosing. Vardenafil can cause a sudden drop in blood pressure. When combined with other specific medications, your blood pressure can drop to particularly unsafe levels, resulting in dizziness, fainting, and even a heart attack or stroke. Seek immediate medical help if this occurs. Indigestion or Dyspepsia (uncomfortable feeling in the uppermiddle part of your stomach) Indigestion or Dyspepsia (uncomfortable feeling in the uppermiddle part of your stomach) These side effects generally decrease over time, going away altogether within a few hours.