L., Wrishko, R. E., & Mitchell, M. I. British Journal of Clinical Pharmacology, 61(3), 280-288. Assessment of combination therapies vs monotherapy for erectile dysfunction: A systematic review and meta-analysis.
(2006). Practice pointer: Treating erectile dysfunction when PDE5 inhibitors fail. BMJ : British Medical Journal, 332(7541), 589-592. Efficacy of continuous dosing of tadalafil once daily vs tadalafil on demand in clinical subgroups of men with erectile dysfunction: A descriptive comparison using the integrated tadalafil databases. The Journal of Sexual Medicine, 13(5), 860. Efficacy and safety of tadalafil 5, 10, and 20 mg in Japanese men with erectile dysfunction: Results of a multicenter, randomized, double-blind, placebo-controlled study. Clinical safety of oral sildenafil citrate (VIAGRATM) in the treatment of erectile dysfunction. International Journal of Impotence Research, 10(2), 69-73. Asian Journal of Pharmaceutical Research (AJPRes.) Sublingual tablets — an updated review. Asian Journal of Pharmaceutical Research, 9, 2231-5691.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 40mg | 10 Pills | 37.79€ 35.99€ | |
| Cialis Generic | 2.5mg | 60 + 4 Pills | 83.43€ 79.46€ | |
| Cialis Generic | 60mg | 120 + 8 Pills | 240.18€ 228.74€ | |
| Cialis Original | 20mg | 22 + 2 Pills | 129.20€ 123.05€ | |
| Cialis Generic | 10mg | 60 + 6 Pills | 105.81€ 100.77€ | |
| Cialis Super Active | 20mg | 180 + 20 Pills | 521.59€ 496.75€ | |
| Cialis Generic | 40mg | 180 + 10 Pills | 277.29€ 264.09€ | |
| Cialis Generic | 60mg | 30 + 2 Pills | 85.33€ 81.27€ | |
| Cialis Generic | 2.5mg | 90 + 6 Pills | 112.43€ 107.08€ | |
| Cialis Generic | 10mg | 270 + 10 Pills | 308.71€ 294.01€ | |
| Cialis Super Active | 20mg | 90 + 10 Pills | 314.14€ 299.18€ | |
| Cialis Original | 20mg | 34 + 2 Pills | 183.99€ 175.23€ | |
| Cialis Original | 20mg | 76 + 4 Pills | 319.19€ 303.99€ |
Substantially increased sildenafil bioavailability after sublingual administration in children with congenital heart disease: two case reports. Journal of Medical Case Reports, 8, 171.
Prescription medications like clomiphene or enclomiphene may prove superior for many men, allowing them to avoid the injections, the fertility risks, and the sometimes wild swings in testosterone levels that come with them.21 22 If you find your T levels are low, you can also reach for nutritional supplements like Innerbody Testosterone Support, a product we created to provide a better set of ingredients, at clinically relevant doses, than we could find anywhere on the market. Ro also makes a testosterone supplement with a similar name (Roman Testosterone Support), which we recommend to men on tight budgets who are okay with slightly fewer ingredients and slightly smaller doses than some of what you’ll find in the Innerbody alternative. You can learn more about these and other competing products in our complete guide to testosterone boosters. Shockwave, or acoustic wave, treatment is relatively new to the ED space, at least for most men. Despite some confusion, shockwave therapy does not involve electrical stimulation.
Shockwave treatment uses a powerful motor to deliver targeted shockwaves to tissue. Different frequencies of shockwave will penetrate to specific depths, with treatments targeting ED designed to reach the corpus cavernosum, where they can stimulate and improve blood flow.23 In most cases, these treatments are performed in a clinic under the care of a trained urologist, as the available literature still characterizes low-intensity extracorporeal shockwave therapy as investigational according to most major urology guidelines (AUA, EAU ). Still, some companies have begun producing at-home devices you can use to administer shockwaves yourself. Most of the at-home shockwave devices we’ve seen are either too weak to be effective, too dangerous to recommend, or both. The Phoenix Shockwave device stands out among them as a viable option if you’re wary of attending in-person sessions with a urologist or your insurance won’t cover the expense.
However, it’s critical to note that no FDA-approved shockwave treatment device for home use 60 mg cialis currently exists for the treatment of ED. Home use should be considered experimental and approached with caution. McMahon, C. N., Smith, C. J., & Shabsigh, R. Sildenafil in the treatment of erectile dysfunction: An overview of the clinical evidence. Clinical Interventions in Aging, 1(4), 403-414. Vardenafil for the treatment of erectile dysfunction: An overview of the clinical evidence. Clinical Interventions in Aging, 4, 463-472. The efficacy and safety of avanafil during a treatment of male erectile dysfunction: A systematic review and meta-analysis of randomized controlled trials.
Once-daily tadalafil is not only for erectile dysfunction, but has also been FDA-approved for lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH) — a common comorbidity in older men. It’s especially useful for men who have both erectile dysfunction and urinary symptoms caused by BPH, since it provides both benefits with a single medication. Ro offers on-demand and daily tadalafil, but its Cialis is only available in on-demand doses and quantities (and for a similarly high price as brand-name Viagra). These are all available as traditional tablets, but Ro recently added a daily tadalafil gummy to its lineup. As is the case with sildenafil, several providers offer better prices on tadalafil, including Hims and BlueChew.
Some research suggests that up to 40% of ED cases are psychogenic, meaning they originate from a psychological source and not a physical one.17 These are typically diagnosed after ruling out physical conditions through thorough history-taking, physical exams, and routine lab work. In some of these cases, PDE5 inhibitors may still be effective in psychogenic ED and can serve as a temporary aid while patients undergo psychological therapy. They could offer a bridge for men seeking psychological treatment, helping restore sexual function during the course of psychological treatment. There are also prescription approaches to anxiety and depression available, as both issues can contribute to or even cause ED.18 Access to talk therapy and psychiatry has never been easier, thanks to a revolution in telehealth services that got a big boost in the last few years. Now, through companies like BetterHelp, Talkspace, and Cerebral, men can seek cognitive behavioral therapy, prescription medication, and more without leaving home.
And pricing is such that many men without insurance can also get the help they need. Related:The Best Online Therapy in 2026 According to Dr. Kelepurovski, “While teletherapy can be super convenient, it is still valuable for men with ED and co-comorbid depression/anxiety to have physician oversight to manage their overall psychological and sexual health. Psychogenic erectile dysfunction is very common and often undiagnosed, and for these patients, improving emotional or psychological underlying factors, with or without medical support, can result in long-term resolution." Low testosterone (hypogonadism) is a potential cause of ED, especially when considering other symptoms like a reduced libido, fatigue, or mood changes.19 If you also find yourself with low libido, low energy, excess body fat, or moodiness, your testosterone levels might be low.20 You can take convenient at-home tests to determine if you have low testosterone, and once confirmed by a physician, you can treat it with everything from testosterone replacement therapy (TRT) to prescription pills and even nutritional supplements. Testosterone Replacement Therapy (TRT) is a more extensive treatment, usually limited to clinically established hypogonadism in men, as it often involves injecting yourself with testosterone cypionate or a similar analog. Therapeutics and Clinical Risk Management, 19, 629-644. Open Access Macedonian Journal of Medical Sciences [Internet]. The Urologic clinics of North America, 28(2), 269-278. Does testosterone have a role in erectile function?.
The American Journal of Medicine, 119(5), 373-382.
Rivas, A.
| Month | Lowest Price (USD) | Highest Price (USD) | Average Price (USD) |
|---|---|---|---|
| Jan 2026 | 40 | 50 | 45 |
| Feb 2026 | 42 | 48 | 45 |
| Mar 2026 | 39 | 47 | 43 |
| Apr 2026 | 41 | 49 | 45 |
| May 2026 | 40 | 50 | 45 |
M., Mulkey, Z., Lado-Abeal, J., & Yarbrough, S.
This is one of the two drugs in Ro Sparks, and it’s the generic form of Viagra.13 Sildenafil is typically taken approximately 30–60 minutes before anticipated sexual activity and has an effective duration of action of 4–6 hours. It’s available as a tablet, chewable, or lozenge from different companies, with the tablets from Strut Health being among the best-priced and the chewables from BlueChew being among the most convenient. Sildenafil doesn’t last as long as tadalafil, but some men prefer something that’s out of their systems when they don’t need it anymore. This is the other drug in Ro Sparks, and it’s the generic form of Cialis.14 Tadalafil’s effects can persist for up to 36 hours, making it a suitable choice for patients seeking flexibility in timing and adding a layer of convenience that sildenafil can’t match. Tadalafil is also available as a daily medication at a lower dose than the on-demand version.
Like sildenafil, it’s available in various forms, including as a daily gummy from Ro. It has about the same duration of action, but it’s a little better at specifically targeting PDE5 without collaterally affecting other PDE enzyme groups.15 As a result, vardenafil usually has a lower incidence of certain side effects, though it has about the same cardiovascular risk profile. It’s also often more expensive than either sildenafil or tadalafil. Avanafil has the lowest side effect risk of all the drugs similar to sildenafil, likely due to its selectivity for PDE5. However, it’s only available in its branded form (Stendra) at this time, as the patent on the drug is still active.16 You can get Stendra from Hims, but most other telehealth providers don’t stock it.
Sparks is one of Ro’s most recent ED medication offerings. The company has offered traditional ED meds for years, and it’s recently begun expanding that catalog. Here’s a look at some of the alternatives you can choose through Ro, with a little commentary about whether it’s the best place to get them. However, its cost per dose for generics is higher compared to competitors like BlueChew and Strut Health, the former of which delivers its meds as convenient chewables. And brand-name Viagra is prohibitively expensive from Ro and just about every other provider where we’ve seen it offered, even though generic equivalents are therapeutically identical. (2014). Proceedings (Baylor University Medical Center), 27(4), 321-324.
Forgue, S. T., Patterson, B. E., Bedding, A. W., Payne, C. D., Phillips, D. Efficacy of clomiphene citrate versus enclomiphene citrate for male infertility treatment: A retrospective study. Translational Andrology and Urology, 5(6), 834-843.